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M Higaki Selected Research

esonarimod

6/2001KE-298 and its active metabolite KE-758 suppress nitric oxide production by murine macrophage cells and peritoneal cells from rats with adjuvant induced arthritis.
5/2001The new antirheumatic drug KE-298 suppresses monocyte chemoattractant protein (MCP)-1 and RANTES production in rats with adjuvant-induced arthritis and in IL-1beta-stimulated synoviocytes of patients with rheumatoid arthritis.

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M Higaki Research Topics

Disease

3Arthritis (Polyarthritis)
08/2005 - 05/2001
2Neoplasms (Cancer)
03/2020 - 11/2001
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2020
1Chronic Hepatitis C
06/2007
1Body Weight (Weight, Body)
06/2007
1Experimental Arthritis
08/2005
1Neoplasm Metastasis (Metastasis)
11/2001
1Carcinoma (Carcinomatosis)
11/2001
1Stomach Neoplasms (Stomach Cancer)
11/2001
1Rheumatoid Arthritis
05/2001
1Tetanus
04/2001
1Infarction (Infarctions)
01/2000
1Splenic Infarction
01/2000
1Papillary Adenocarcinoma
01/2000
1Pulmonary Infarction
01/2000
1Cerebral Infarction
01/2000

Drug/Important Bio-Agent (IBA)

2esonarimodIBA
06/2001 - 05/2001
1human AZU1 proteinIBA
03/2020
1MicroRNAs (MicroRNA)IBA
03/2020
1eldecalcitol (ED 71)IBA
03/2020
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
03/2020
1hydroxide ionIBA
03/2020
1eIF-2 Kinase (eIF 2 Kinase)IBA
06/2007
1InterferonsIBA
06/2007
1Double-Stranded RNA (RNA, Double Stranded)IBA
06/2007
1Ribavirin (Virazole)FDA LinkGeneric
06/2007
1Collagen Type II (Type II Collagen)IBA
08/2005
1GlucocorticoidsIBA
08/2005
1betamethasone sodium phosphateFDA LinkGeneric
08/2005
1Pharmaceutical PreparationsIBA
08/2005
1glycolic acid (glycolate)IBA
08/2005
1Dihematoporphyrin Ether (Porfimer Sodium)FDA Link
11/2001
1LipopolysaccharidesIBA
06/2001
1KE 758IBA
06/2001
1Nitric Oxide (Nitrogen Monoxide)FDA Link
06/2001
1Antirheumatic Agents (DMARD)IBA
05/2001
1Monocyte Chemoattractant ProteinsIBA
05/2001
1Chemokine CCL5IBA
05/2001
1InterleukinsIBA
05/2001
1Diphtheria Toxoid (Vaccine, Diphtheria)FDA Link
04/2001
1CollagenIBA
04/2001
1beta-ThromboglobulinIBA
01/2000
1SteroidsIBA
01/2000
1Warfarin (Coumadin)FDA LinkGeneric
01/2000
1Ticlopidine (Ticlid)FDA LinkGeneric
01/2000
1Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA
01/2000
1antithrombin III-protease complexIBA
01/2000

Therapy/Procedure

3Therapeutics
03/2020 - 01/2000
1Intravenous Administration
08/2005
1Photochemotherapy (Photodynamic Therapy)
11/2001
1Laser Therapy (Surgery, Laser)
11/2001
1Dye Lasers
11/2001